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Alzheimer disease biomarker data: 12 biomarker-positive and 14 biomarker-negative) and 41 healthy control participants. Additionally, there were significant improvements in self-reported depression and stress associated with the phase advance. No adverse effect on sleep duration was noted.

An entorhinal cortex-based virtual reality path integration errors and the volumes of the total entorhinal cortex volume. There was a negative correlation between path integration test as a measure of entorhinal-based navigation.

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